Clinatec

Developed WIMAGINE, a 64-electrode wireless epidural recorder used for exoskeleton control and in the brain–spine interface.

Interface category

Electrocorticography

Signal

Local field potentials, including high-gamma activity

Invasiveness

Invasive

Recording / stimulation

Recording

Device

WIMAGINE — Wireless epidural recorder set into the skull

Channels

64 electrodes per implant

Regulatory status

Investigational

Main use cases

Move

Works with

Clinatec, CEA / CHU Grenoble Alpes · EPFL / Lausanne University Hospital

Shown in people

A participant with tetraplegia controlled a four-limb exoskeleton through two wireless 64-electrode epidural recorders over 24 months (peer reviewed, 2019).

Still an aim

Clinical use beyond individual participants.

What stands in the way

Numbers: its registered studies plan single-digit enrolment.

On record here: 2 registered studies · 8 participants planned or enrolled · 2 peer-reviewed papers

Clinatec's epidural approach sits between surface ECoG and non-invasive recording: outside the dura, fully implanted and wireless years before commercial systems were. It demonstrates that modest channel counts can drive clinically meaningful movement when paired with the right effector. The evidence is from single participants, and its registered studies plan single-digit enrolment.

1. 24 May 2023

   The same recording implants form the cortical half of the brain–spine interface.

   Peer reviewedLorach H et al., Nature

2. 3 Oct 2019

   A participant with tetraplegia controls a four-limb exoskeleton using two wireless epidural recorders over 24 months.

   Peer reviewedBenabid AL et al., The Lancet Neurology

• STIMO-BSI

  Brain–spine interface linking cortical recordings to spinal stimulation for walking.

  FeasibilityActive, not recruiting

  3 estimatedNCT04632290

• Brain computer interface: neuroprosthetic control of a motorized exoskeleton

  Wireless epidural recorders for exoskeleton control.

  FeasibilityRecruiting

  5 estimatedNCT02550522

• 2023
  Walking naturally after spinal cord injury using a brain–spine interface

  Lorach H et al. · Nature

• 2019
  An exoskeleton controlled by an epidural wireless brain–machine interface in a tetraplegic patient: a proof-of-concept demonstration

  Benabid AL et al. · The Lancet Neurology

• ECoGFeasibility

  ONWARD Medical

  Spinal cord stimulation therapies, with a brain–spine interface in development.

• ECoGFirst-in-human

  CorTec

  A fully implanted closed-loop system that both records from and stimulates the cortical surface.