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The BCI Briefing

Company profileNeural interface

INBRAIN Neuroelectronics

Graphene-based cortical interfaces for high-resolution recording and stimulation.

Location
Barcelona, Spain
Founded
2019
Class
Neural interfaceGraphene electrode arrays aimed at closed-loop therapy; human use so far is intraoperative mapping.Not counted among core BCI companies.
Funding stage
Series B
Sources last checked
6 Oct 2026

What they are building

Develops graphene electrode arrays that the company gives as 10 micrometres thick, intended for brain mapping and closed-loop therapy. Their first use in people was during tumour surgery at Salford Royal Hospital in Manchester.

Signal
ECoG: Local field potentials, including high-gamma activityECoG + stim: Field potentials out; electrical pulses in
Invasiveness
Invasive
Recording / stimulation
Recording and stimulation
Device
Graphene cortical interface — Thin-film graphene electrode array on the cortical surface
Regulatory status
Investigational; first-in-human study completed
Main use cases
Restore, Monitor
Works with
University of Manchester / Northern Care Alliance

Where they are clinically

First-in-human

The first use of a device in a small number of people, focused on safety.

Access today

Experimental human research

Demonstrated in a small number of research participants. Not an established treatment.

Shown in people
Graphene electrodes used for brain mapping during surgery in ten participants. The first-in-human study was completed in June 2026 and has not been published.
Still an aim
Closed-loop therapy from a chronically implanted graphene array.
What stands in the way
Chronic evidence: whether graphene keeps its electrical advantage inside the body over years.

On record here: 1 registered study · 10 participants planned or enrolled · 0 peer-reviewed papers

This technology remains experimental and is not an established treatment. Access is limited to registered clinical studies.

Why this company matters

INBRAIN is a materials bet: that graphene's charge-injection and thinness translate into better stimulation and recording at small contact sizes. A completed ten-participant first-in-human study is a meaningful step; published results will show whether the material advantage holds in people.

Key milestones

  1. 24 Jun 2026

    First-in-human study completes with ten participants.

    First-in-human clinical investigation of graphene electrodes for brain mapping · NCT06368310

  2. 29 Oct 2024

    Series B of $50M led by imec.xpand. The release also states an FDA Breakthrough Device designation for Parkinson's disease.

    imec (press release)

  3. 6 Aug 2024

    First-in-human investigation of graphene electrodes for brain mapping begins in Manchester.

    First-in-human clinical investigation of graphene electrodes for brain mapping · NCT06368310

Clinical programmes

Funding history

  • 29 Oct 2024$50MSeries B · led by imec.xpand

Investors namedimec.xpand

Rounds in the Briefing’s sample only; not a complete funding history.

IP and patents

Filings touch 5 of the 11 layers, most often interface and electrodes (11 of 12 families) and stimulation (9).

12
patent families identified and counted as BCI
2020
earliest first filing among them
11
first filed since 2021; the latest years are incomplete
5 of 12
include a granted member, of those whose family record was read

Across the stack: families by layer

Themes, by number of families: electrodes and arrays (11), stimulation (9), peripheral interfaces (7), materials and coatings (4), packaging and hermeticity (4), wireless telemetry (4). A family can carry several.

Published in: United States (8), China (5), Spain (4), Japan (4), Brazil (1), counted over the 12 families whose full record was read.

6 more families counted

Families found for INBRAIN Neuroelectronics in the EPO’s worldwide database, grouped so that one invention counts once. A filing shows what a company sought to protect. It does not show that the technology was built, is in a product, or works in people, and themes are read from titles, abstracts and classes, not from the claims. How to read this

Competitive context

Sources

  1. 01

    INBRAIN Neuroelectronics raises $50M Series B to advance graphene-based brain-computer interface technology (opens in a new tab)

    Company reportedimec (press release)29 Oct 2024Checked against source 6 Oct 2026

    A release carried by the parent of the round's lead investor. It states the round, the first human use at Salford Royal Hospital in Manchester, the 10-micrometre thickness and an FDA Breakthrough Device designation for Parkinson's disease.

  2. 02

    ClinicalTrials.gov NCT06368310 (opens in a new tab)

    Clinical registryClinicalTrials.gov30 Jun 2026Checked against source 3 Oct 2026

    Registry record last updated 2026-06-30.