Speech · Decoding & AI
A high-performance speech neuroprosthesis
- Authors
- Willett FR … Henderson JM12 authors
- Institution
- Stanford University
- Publication
- NatureNature 2023;620(7976):1031–1036 · 23 Aug 2023
- Status
- Primary source
The 60-second view
- What problem?
- Speech BCIs had not reached accuracies usable for unconstrained sentences over a large vocabulary.
- What did they do?
- Recorded spiking activity from intracortical arrays in a participant with ALS and decoded attempted speech to text.
- What changed?
- Reported the first successful large-vocabulary decoding and more than tripled the previous speed record.
- Why does it matter?
- It established that a small patch of cortex carries enough articulatory detail for open-vocabulary speech, years after speech was lost.
Method
- Participants
- One person with ALS who can no longer speak intelligibly
- Interface
- Intracortical microelectrode arrays in speech motor cortex
- Signal
- Intracortical spiking activity
- Task
- Attempted speech of prompted sentences
- Decoder
- Recurrent neural network to phonemes, with a language model
Results
- 9.1%
- Word error rate, 50-word vocabulary
- 23.8%
- Word error rate, 125,000-word vocabulary
- 62 words/min
- Decoding rate
- Natural conversation is about 160
Strength of evidencePeer reviewed, one participant. The underlying data were released and now anchor a public benchmark.
Figures are quoted from the published abstract and were checked on 3 Oct 2026.
Limitations
- One participant.
- Roughly one word in four was wrong at the large vocabulary size.
What this could enable
A shared dataset that other groups have used to cut word error rates further without new surgery.
Primary source
- 01
Willett FR et al. Nature 2023;620(7976):1031–1036 (opens in a new tab)
Peer reviewedNature23 Aug 2023Checked against source 3 Oct 2026
DOI 10.1038/s41586-023-06377-x