Non-invasive · Decoding & AI
A generic non-invasive neuromotor interface for human-computer interaction
- Authors
- Kaifosh P … Reardon TR3 authors
- Institution
- See publication
- Publication
- NatureNature 2025;645(8081):702–711 · 23 Jul 2025
- Status
- Primary source
The 60-second view
- What problem?
- High-bandwidth neural input had needed invasive interfaces and decoders built for one person.
- What did they do?
- Collected sEMG from thousands of participants and trained generic models for gestures, navigation and handwriting.
- What changed?
- Demonstrated out-of-the-box generalisation across users, improved further by personalisation.
- Why does it matter?
- Scale of training data, not sensor resolution, delivered generalisation. Implanted BCI is now testing the same idea.
Method
- Participants
- Thousands of consenting participants for training; separate test users
- Interface
- Dry-electrode sEMG wristband
- Signal
- Surface electromyography at the wrist
- Task
- Continuous navigation, discrete gestures and handwriting
- Decoder
- Generic neural-network decoders, optionally personalised
Results
- 0.66 target acquisitions/s
- Continuous navigation
- 0.88 detections/s
- Discrete gestures
- 20.9 words/min
- Handwriting
- 16%
- Gain from personalisation
- Handwriting models
Strength of evidencePeer reviewed; large participant pool; authored by the developer.
Figures are quoted from the published abstract and were checked on 3 Oct 2026.
Limitations
- Requires intact motor pathways to the wrist.
- Reads muscle activation, not brain activity.
What this could enable
Neuromotor input as an everyday interface, and a template for cross-subject decoding.
Primary source
- 01
Kaifosh P et al. Nature 2025;645(8081):702–711 (opens in a new tab)
Peer reviewedNature23 Jul 2025Checked against source 3 Oct 2026
DOI 10.1038/s41586-025-09255-w