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The BCI Briefing

Non-invasive · Decoding & AI

A generic non-invasive neuromotor interface for human-computer interaction

Authors
Kaifosh P … Reardon TR3 authors
Institution
See publication
Publication
NatureNature 2025;645(8081):702–711 · 23 Jul 2025
Status
Primary source

The 60-second view

What problem?
High-bandwidth neural input had needed invasive interfaces and decoders built for one person.
What did they do?
Collected sEMG from thousands of participants and trained generic models for gestures, navigation and handwriting.
What changed?
Demonstrated out-of-the-box generalisation across users, improved further by personalisation.
Why does it matter?
Scale of training data, not sensor resolution, delivered generalisation. Implanted BCI is now testing the same idea.

Method

Participants
Thousands of consenting participants for training; separate test users
Interface
Dry-electrode sEMG wristband
Signal
Surface electromyography at the wrist
Task
Continuous navigation, discrete gestures and handwriting
Decoder
Generic neural-network decoders, optionally personalised

Results

0.66 target acquisitions/s
Continuous navigation
0.88 detections/s
Discrete gestures
20.9 words/min
Handwriting
16%
Gain from personalisation
Handwriting models

Strength of evidencePeer reviewed; large participant pool; authored by the developer.

Figures are quoted from the published abstract and were checked on 3 Oct 2026.

Limitations

  • Requires intact motor pathways to the wrist.
  • Reads muscle activation, not brain activity.

What this could enable

Neuromotor input as an everyday interface, and a template for cross-subject decoding.

Primary source

  1. 01

    Kaifosh P et al. Nature 2025;645(8081):702–711 (opens in a new tab)

    Peer reviewedNature23 Jul 2025Checked against source 3 Oct 2026

    DOI 10.1038/s41586-025-09255-w